Recent progress in micro and nano-encapsulation of bioactive derivatives of the Brazilian genus Pterodon.
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2021
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Resumo
In the last few decades, utilization of medicinal plants by the pharmaceutical industry has led to the identifi-
cation of many new bioactive compounds. The genus Pterodon, native of the Brazilian Flora, is known for the
therapeutic properties attributed to its species, which are widely used in popular medicine for their anti-
inflammatory, anti-rheumatic, tonic, and depurative properties. The intrinsic low water solubility of the plant
derivatives from the genus, including diterpenes with vouacapane skeletons that are partially associated with the
pharmacological activities, impairs the bioavailability of these bioactive compounds. Recent studies have aimed
to encapsulate Pterodon products to improve their water solubility, achieve stability, increase their efficacy, and
allow clinical applications. The purpose of this paper is to review recent research on the use of nanotechnology
for the development of new products from plant derivatives of the Pterodon genus in different types of micro- and
nanocarriers. Therapeutic properties of their different products are also presented. Finally, an update about the
current and future applications of encapsulated formulations is provided.
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Encapsulation, Polymeric nanoparticle, Lipidic nanoparticle, Terpenes, Natural products
Citação
LEMOS, J. de A. et al. Recent progress in micro and nano-encapsulation of bioactive derivatives of the Brazilian genus Pterodon. Biomedicine & Pharmacotherapy, v. 143, 2021. Disponível em: <https://www.sciencedirect.com/science/article/pii/S0753332221009215?via%3Dihub>. Acesso em: 11 out. 2022.